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Therapeutic (53)
Tech. Category Tech. ID Technology Summary Available? TTO Contact
Drug Target CU1250H The Use Of Inhibitors Of Cyclin A1 Activity For Cancer Therapy Yes, download Brian Bellesheim
Drug Target CU1448H Description of a Full B. Subtilis Primasome Dependent Replication System No, contact TTO Brynmor Rees
Drug Target CU2057H Identification of gene targets that cooperate with Flt3 inhibition in the treatment of acute myeloid leukemia No, contact TTO Heather Callahan
Drug Target CU2283H New, Improved N-Terminal Dimerization Methods with Bis-imidate-and bis-thioimidate derivatives No, contact TTO Paul Tabor
Drug Target CU2460B Development of TTK/Mps1 Kinase Inhibitors For the Treatment of Human Cancers Yes, download Brynmor Rees
Drug Target CU2511H AMPD2 Inhibitors for Treatment/Prevention of Obesity, Diabetes, Metabolic Syndrome, Fatty Liver and Hypertension Yes, download Paul Tabor
Drug Target CU2580H Inhibition of Fructokinase Isoforms to Treat Obesity, Metabolic Syndrome and Diabetes Yes, download Paul Tabor
Drug Target CU3198B Therapeutically targeting the BH3 domain of Hepatitis B Virus X protein and its host targets, Bcl-2 and Bcl-xL, to treat chronic Hepatitis B Virus. Yes, download Brynmor Rees
Drug Target CU3206H Therapeutically targeting CtBP in cancer and inflammation Yes, download Heather Callahan
Drug Target FD283H DNA Sequence Encoding Human Cystathionine B-Synthase No, contact TTO Heather Callahan
Drug Target FD284H Advanced Technique for Identifying Pathogenic Gene Mutations Related to Enzymatic Diseases Yes, download Heather Callahan
Drug Target IR436H Detecting and Treating Heart Failure No, contact TTO Paul Tabor
New Use or Method of Treatment 7077H Diagnosis and Treatment of Myocardial Failure using Myosin Heavy Chains Yes, download Paul Tabor
New Use or Method of Treatment CU1267H Diagnostic And Therapeutic Potential Of Novel Leukemia-Specific MER Proteins In Leukemia And Lymphoma Yes, download Heather Callahan
New Use or Method of Treatment CU1881H Investigation of Epigenetic Modulation in Multiple Myeloma No, contact TTO David Poticha
New Use or Method of Treatment CU2065H Anti-Inflammatory Potential of HIF Prolyl Hydroxylases No, contact TTO Brian Bellesheim
New Use or Method of Treatment CU2262H Timed-Release Formulations of GTS-21 and Related Arylidene-Anabaseines No, contact TTO Paul Tabor
New Use or Method of Treatment CU2650H Nebivolol Treatment in Pediatric Heart Failure Patients No, contact TTO Doreen Molk
New Use or Method of Treatment CU2745H A New Anti-Androgen, MDV3100, Can be Used as a Therapeutic Anti-Androgen or Anti-Estrogen Agent to Block Hormone-Dependent Growth in Breast Cancer No, contact TTO Brian Bellesheim
New Use or Method of Treatment CU2761H COPD Prognosis, Diagnosis and Therapy: A Personalized Medicine Approach Yes, download Heather Callahan
New Use or Method of Treatment CU2787H Use of Photosensitive Agents and LDL Receptor Ligands to Target the Aqueous Outflow System of the Eye and Decrease Intraocular Pressure No, contact TTO Heather Callahan
New Use or Method of Treatment CU2828H Cystathionine for Treatment of Liver and Kidney Injury, Cardiovascular Protection & Chemotherapy Potentiation (COMBINED WITH CU2280H and CU2827H, UPDATE CU2828H) Yes, download Heather Callahan
New Use or Method of Treatment CU3030B Trehalose as a treatment for vascular dysfunction, inflammation, oxidative stress and overall physical dysfunction (reduced exercise capacity and low physical activity levels) No, contact TTO Molly Markley
New Use or Method of Treatment CU3044H Combination of Bendamustine and the HDAC Inhibitor SNDX-275 Enhances Apoptosis and DNA Damage Response in Multiple Myeloma Cells No, contact TTO David Poticha
Novel Chemical Entity CU1234H A New Approach to Treat Pancreatic Cancer Yes, download Heather Callahan
Novel Chemical Entity CU1258H Novel Mer and Axl Compounds for the Diagnosis and Treatment of Cancer Yes, download Heather Callahan
Novel Chemical Entity CU1323H Rational Design of Alpha-Helical Antimicrobial Peptides with Enhanced Activities and Specificity/Therapeutic Index Yes, download Paul Tabor
Novel Chemical Entity CU1435B Doxazolidine, Doxazolidine Derivatives, and Targeted Doxazolidines for the Treatment of Cancer Yes, download Dipika Singh
Novel Chemical Entity CU1626H Hsp90 Inhibitors. Modification of Toxicity Yes, download Heather Callahan
Novel Chemical Entity CU1635H Collection and Activation of Mixtures of TGFbeta Superfamily Molecules from Expired Human platelets for use as a Proangiogenic Compound for Stimulation of Wound Healing and Other Forms of Therapeutic Angiogenesis Yes, download Heather Callahan
Novel Chemical Entity CU1692H Inhibition of the Axl Tyrosine Kinase as Biologically Targeted Cancer Therapy Yes, download Heather Callahan
Novel Chemical Entity CU1693H Stimulation of Apoptosis Using Novel Potent Tight Junction Protein Modulators Yes, download Heather Callahan
Novel Chemical Entity CU1933H Potent Cell-Penetrating CaMKII Inhibitors, and CaMKII as Drug Target in Stroke, Traumatic Brain Injury, Neurodegenerative Diseases, and Addiction. Yes, download Heather Callahan
Novel Chemical Entity CU2374H Antimicrobial Peptides to Treat Bacterial Infections Yes, download Paul Tabor
Novel Chemical Entity CU2376H A Specific Peptide to Control Inflammation Including Autoimmune Derived Inflammation Yes, download Paul Tabor
Novel Chemical Entity CU2399H Rational Design and Synthesis of Novel Flurbiprofen Amide Small Molecules for Treatment of Non Small Cell Lung (NSCL) Cancer Yes, download Doreen Molk
Novel Chemical Entity CU2427B Novel Small-Molecule Agents That Potentiate Opioid Analgesia Yes, download Dipika Singh
Novel Chemical Entity CU2548H Sorbitol Inhibition for Treatment of Diabetic Eye Disease No, contact TTO Heather Callahan
Novel Chemical Entity CU2587B Histone Demethylase Inhibitors No, contact TTO Brynmor Rees
Novel Chemical Entity CU2633H MicroRNAs for Heart and Muscle Wasting Disease Yes, download Brian Bellesheim
Novel Chemical Entity CU2640H Small molecules that inhibit Eya's phosphatase activity and the Six1/Eya interaction Yes, download Brian Bellesheim
Novel Chemical Entity CU2665H Urate Transporter Inhibitors: Compounds Designed For Uricosuric Action No, contact TTO Paul Tabor
Novel Chemical Entity CU2709B Small Molecule Inhibitors of Toll-Like Receptor 3 for Treatment of Inflammatory and Infectious Diseases Yes, download Dipika Singh
Novel Chemical Entity CU2737H Novel silicon-containing small molecules for treatment of lung and prostate cancer Yes, download Doreen Molk
Novel Chemical Entity CU3114B Small Molecule Antagonists of the TLR1/TLR2 Complex for Treatment of Inflammatory & Infectious Diseases Yes, download Dipika Singh
Pharmacophore CU2637H Multifunctional Prodrugs for the Treatment of Malignant Glioma No, contact TTO Heather Callahan
Stem Cell or Regenerative Medicine 7060H Transplantation of Immortalized Human Dopamine Cells to Improve Neurological Deficits / Fetal neurons as treatment for parkinson's disease. Includes TRM: Rat Cell Line No, contact TTO Brian Bellesheim
Stem Cell or Regenerative Medicine CU1687B Engraftment and Survival of Adult Skeletal Muscle Stem Cells Yes, download Dipika Singh
Stem Cell or Regenerative Medicine CU2207H Human induced-pluripotent stem cells generated with adenoviral gene transfer No, contact TTO Heather Callahan
Stem Cell or Regenerative Medicine CU2425H Autologous CD117+Progenitor Cell Therapy for Allograft Prolongation Yes, download Heather Callahan
Stem Cell or Regenerative Medicine CU2676H NanoCardioLab: Exploring the Heart at the Micro-and Nanoscale No, contact TTO Doreen Molk
Vaccine 7100H Disassembly of Papillomaviruses Yes, download Brynmor Rees
Vaccine CU2295H Develop vaccine to produce antibodies to primary autoimmune trimolecular complex (class II MHC-autoantigen-T cell receptor) for prevention of auto immunity Yes, download Heather Callahan
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